A network of 22 Arab-American charities say they will no longer accept donations from Lowe's.
The announcement was in response to the home improvement chain's decision to pull its advertising schedule on The Learning Channel's reality TV series "All-American Muslim."
The series follows the lives of five Muslim families in and near the Detroit suburb of Dearborn, Mich.
The National Network for Arab American Communities said the retailer's decision contradicts their values.
Lowe's executives said the show became a "lightning rod for people to voice complaints" and they did not want their company caught in the middle of controversy.
The Florida Family Association, a conservative Christian group, recently launched an e-mail campaign, complaining to the Moorhead, N.C.-based retailer that the show hides Islam's threat to American liberties and traditional values.
Meanwhile, the travel website Kayak.com has announced it has cancelled all of its advertising on the TLC series.
A Kayak spokesman said the company's decision is not because of backlash from the Florida Family Association, but because TLC was not "up front about the nature of the show."