Much of the U.S. on Tuesday was facing some sort of winter storm watch, warning or advisory.
The system has already wrought havoc in the South this week, causing cities like Atlanta to virtually shut down.
The city has received a record-breaking seven inches of snow so far. And with just eight snow plows in operation, most of the snow will stay on city streets.
Only 40 flights left Atlanta's Hartsfield-Jackson International Airport on Monday, creating a ripple effect around the country.
"Everything is delayed," stranded airline travler Dontae Keyes said. "Looks like the pipeline from here to Atlanta... is shut down, so we're going to be here for a couple of days."
The storm broke more than half a dozen snow records across the Deep South.
The system was expected to move up the East Coast where it may combine with a Midwest system that's expected to hit Washington, D.C., New York City and Boston.
The storm could deposit 5 to 8 inches of snow in Philadelphia, approximately 4 inches in northern New Jersey, and 2 to 6 inches in southern Delaware from Tuesday afternoon into Wednesday morning, according to the National Weather Service.