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Build a Better Gut to Prevent Liver Disease, Cancer, Alzheimer's and More

Build a Better Gut to Prevent Liver Disease, Cancer, Alzheimer's and More Read Transcript

- [Lorie Johnson] Shocking asit may sound, when a person

becomes sick and dies, toooften, doctors find the

trouble started in the intestines,

because of a disruption in bacteria.

Over the last decades,scientists in labs like this

have been researching theimpact of the gut microbiome

on all types of diseases.

What they've discovered isthe good and bad bacteria

in our bodies has a muchmore profound impact

than previously thought.

Doctor J Bajaj leads a research team at

Virginia Commonwealth University.

He says bacteria living in our intestines

dramatically influenceseach aspect of our health,

literally from head to toe.

- [Dr. Bajaj] Their potentialis still being unraveled,

to the point that even 10years is too little for us

to even scratch the surfaceof the amount of complexity

and the potential thatwe have, both for good

and for harm, in the gut microbes.

- [Lorie] Harm, such asliver disease, one of the

leading causes of death and disability.

- It goes from the spectrum of hepatitis,

obesity induced liver disease,alcohol, all the way to

end stage with cancer,as well as cirrhosis.

- [Lorie] Dr. Bajaj saystoo much bad bacteria

causes inflammation.

- Inflamed liver doesn'tdo its job very well,

the gut gets more inflamed,and this unfortunately

leads to the cycle thatpatients find themselves into

liver disease without knowing it.

- [Lorie] And it's notjust that problem that can

sneak up on someone.

- There are a number ofdiseases that have been linked

to aberrations in the gut microbiome.

- [Lorie] Johns Hopkins'gastroenterologist,

Dr. Gerard Mullin, author of"The Gut Balance Revolution",

says folks need to know,intestinal problems can

lead to cancer, and otherlife-threatening issues.

- What's most alarmingis that there are people

out there who have rheumatoidarthritis, some kind of

autoimmune disease, andcardiovascular disease that

may have a gut condition thatis silent and is the cause.

- [Lorie] He says, whilewe may seem okay when we're

younger, it eventually catches up to us.

- When we reach our 50's, 60's on up, then

all of a sudden it becomesmore sensitive to the

environment and less stable.

So in particular, theelderly are more susceptible

to variations in the environment that may

disturb the microbiome.

- [Lorie] The ClevelandClinic's Dr. Gail Cresci says

the gut also profoundlyaffects thoughts and feelings.

All thanks to the gut-brainaxis, a well-traveled

pathway between the mind andthis crucial part of the body.

- Gut bacteria secretedifferent by-products,

and some of the thingsthat they secrete are

neurotransmitters thatleave the intestinal tract,

and signal to the brainand these are things like

serotonin and dopamine, andwe know those then become

into the bloodstream and can get into

the brain and help affect mood.

So a lot of anxiety disorders,depression are related

with alterations in gut microbiota.

- [Lorie] Also Parkinson's,autism, Alzheimer's,

and multiple sclerosis.

An unhealthy gut can even keepdrugs from doing their jobs.

- [Dr. Cresci] So if you'retaking an oral medication,

that's being processedby your gut microbiome,

and if you think about howsome people are responders

to medication and somepeople aren't, it could be

because they have alterationsin their gut microbiome

then the other person doesn't.

- This is the MayoClinic's anaerobic chamber,

where scientists growand study bacteria that

die when exposed to oxygen.

Believe it or not, wehave a lot of anaerobic

bacteria in our bodies,because a good portion of

our intestines are oxygen free.

Researchers here say theright kind of bacteria means

the lining of our intestinescontains tiny, helpful

holes that allow microscopicnutrients into our bodies.

Too much bad bacteria, however,causes those holes to grow.

- Which means it allows morethings to pass through it,

things which are not desirable.

And yes, I mean there'sa lot of diseases like

Celiac disease,inflammatory bowel disease,

where the gut lining is not as robust.

- [Lorie] Dr. Mark Hyman agrees.

Adding that when large particles leak out,

the immune system sees themas invaders and attacks them.

- [Dr. Hyman] Well, we've hada lot of insults to our gut,

and that leads to disturbancesin our own gut microbiome,

that creates breakdown inour gut lining, that creates

a leaky gut, that createsinflammation, that's

linked to almost all diseases.

- [Lorie] In his book,"Food", Dr. Hyman outlines

how to repair a leaky gut.

- [Dr. Hyman] We need tounderstand how to restore the

gut when it probiotics,and fiber and prebiotics.

It's a massive publichealth problem, and I think

it's led to a lot of other issues.

- Lorie's here with us.

Lorie, it's amazing, howmany doctors really know

about what you're talking about here?

- More and more every day.

I went to the leading healthcenters around the country.

The Cleveland Clinic, theMayo Clinic, Johns Hopkins,

VCU, and they all havevery robust microbiome

research going on.

It's a very new field, but it is on fire.

This is where it's at.

- Now we've got all theselittle things in our stomach.

More of, you say it'strillions of them, trillions.

- Right.

- Alright. What kills them?

- Well, we're going totalk about that tomorrow,

and tomorrow's episode,save the best for last,

is all about all the terriblethings that we do to destroy

our gut microbiome, and justto give you a little preview,

antibiotics, you alreadymentioned that, a bad diet,

being born a certaintype of way, C-sections,

I hate to say that, but it'strue, formula vs. breastmilk,

we'll get into all thedetails of what we do

to destroy our gut.

But as we were talkingabout today, one of the main

effects of a bad gutis called a leaky gut,

and so many people suffer from this.

I brought a little demonstration.

This is what a healthy gutlooks like, it's semi-permeable.

It has tiny little holes init to let good nutrients out.

But if you mess up your gutmicrobiome, what happens

is some of these holes becomelarge, see how large that is?

- [Pat] Yeah, yeah, okay.

- And big proteins sneakout of your gut lining and

into your body, whichcauses an immune reaction,

it causes your immunesystem to activate, and

causes all kinds of awfulinflammation, not to mention

autoimmune diseases.

- [Pat] So the body treatswhatever is leaking from your

gut as an invader.

- Absolutely, if it's too big.

- Yeah.

- I mean, our intestinallining are semipermeable,

they have tiny littleholes, and that's fine.

- [Pat] What creates these holes?

- Bad gut bacteria.

- Really?

- Bad lifestyle, yes.

So it's when the good and the bad bacteria

are not in harmony.

- Take an average 10year old child, what does

he or she eat that isscrewing up the gut biome?

- Well, mostly sugar, and antibiotics.

These antibiotics, by verydefinition, kill bacteria.

That's what antibiotics do.

And it wasn't untilvery, very recently that

we realized we need a lot of our bacteria.

How many decades have webeen associating the word

'bacteria' with something bad?

Turns out, most bacteria are great!

- I've got somethingthat I take right here.

It's called, well you knowabout this, tell me about it.

They say that it's aprebiotic and a probiotic.

Talk about that.

- Right, well the prebioticsare actually the bacterias.

So you want prebiotics,we need prebiotics.

It's a great way to get them through food

or through supplements.

The prebiotics are thebacteria themselves,

the probiotics are what the bacteria eat.

Bacteria are alive, they need to eat.

And what they like to eatare things called prebiotics,

which is basically fiber.

What's fiber? Vegetables, fruit,

not fruit juice, there'sno fiber in fruit juice.

Whole fruits, things likebeans and whole grains like

oatmeal, I know you loveyour oatmeal every morning.

- Absolutely, I had oatmeal, yeah.

- Yeah, so those are what the prebiotics

and the probiotics are.

- [Pat] This comes fromthe Vitamin Shoppe,

and it's called an ultimateprobiotic and it has

billions of units ofprobiotic, now is this good?

Is this okay?

- Well the thing about supplements is

they're not very strictly regulated by the

Food and Drug Administration.

So consumer labs did a studywhere they looked at a bunch of

probiotics and compared whatthey claimed were in them,

and what were actually in them.

And what were actually in themwas not what they claimed.

So sometimes probiotics aregreat, and they're exactly

what they claim to be,and sometimes they're not.

- Are they supposed to berefrigerated or is that a lie?

- Some of them, the best ones,do need to be refrigerated

because they containbacteria that are alive

and need to be refrigerated.

Some probiotics have bacteria in them that

don't need to be refrigerated.

- Is it possible to namea couple of the good ones?

- I like Garden of Life,that's the one that I like.

And what I really like about it is,

you can buy it at healthfood stores and also at

Whole Foods, and it is inthe refrigerated section

but Garden of Life alsois sold at Walmart.

It has the ones that don'tneed to be refrigerated,

so fewer strains of bacteria.

And the reason I likeGarden of Life is because

I happen to know the man who makes them,

Dr. David Perlmutter.

He's actually been aguest on our show before,

he's a man of faith,he's a man of integrity,

he's brilliant, and heknows what he's doing.

So I trust him.

Some of the people who arefeatured in our series this week,

Dr. Mark Hyman, Dr. GerardMullin, they have websites

and you can find their websiteson our website,,

and they recommend different probiotics.

You have to get them inthe mail, you have to order

them online, but they're also good, too.

So if you know somebody whoknows a thing or two about

probiotics, you mightwant to ask them, whether

it's your doctor, obviouslyyou've been consulted on these.

I like the fact that they're organic.

Sometimes probioticsand prebiotics have the

USP seal on them, which means they've been

tested by a reputable organization.

So there are a lot of good ones out there,

and there are a lot ofbad ones out there, too.

- So, the average kid

is being besieged with antibiotics

to kill infection, and he or she is eating

nothing but junk food, Cokes or

how about these sweeteners and stuff?

- Oh, the artificial sweeteners.

Sugar is bad, artificialsweeteners are even worse

for your gut microbiome.

Nevermind the fact that theyhave shown in research studies

that artificial sweetenersmake you gain weight.

And there's a whole big long explanation,

we talked about it a little bit yesterday.

Bottom line is artificialsweeteners are terrible.

And moms think they're doingthe right thing by their kids,

getting them sugar-free,this, that and the other.

But they're really not.

- Like Sweet 'n Low, Splenda, these?

- Right, all the ones thatare generally marketed.

Now, there are a couple goodones out there, but really

you're better to stay awayfrom anything that's sweet.

Just remove the taste ofsweet from your mouth,

after a few weeks, you won't even want it.

You'll eat a grape and think,yikes, that's too sweet!

Because our taste buds do change.

- Now what do we got tomorrow coming up?

- Well tomorrow is reallyperhaps my favorite episode.

We had to set the stageyesterday and today about all,

why the gut microbiome is so important.

Tomorrow is the worst thingsyou can do to your gut.

So these are the thingsthat you have to avoid.

You have to shut off the faucet

before Thursday, we'regonna talk about all

the great things to doto make a healthy gut.

- [Pat] Okay.

- But tomorrow we're gonna talk about all

the ways that we mess it up.

- This little book we made available,

we've already had 17,000people requested it.

- [Lorie] Oh, good!

My prayers are being answered.

(Pat laughs)

- [Pat] It's called "Build a Better Gut",

and we're giving it to you free,

but it's got some nice things.

Tell us what's in here.

- We're talking about whatthe gut microbiome is,

because a lot of people havenever even heard of it before,

so we explain exactly what it is.

It's a mixture of good and bad bacteria.

And how the good bacteriaare so important,

and what happens to you whenyou don't have that right

mixture of good and bad bacteria.

The worst things you can do to your gut,

and the best thingsyou can do to your gut.

So I know a lot of peopleare in the audience thinking,

oh no, how do I remember all of this?

There it is, right there.

All written down and theprice is right, it's free.

- It's free.

And I'm looking forward totomorrow, all the terrible

things that you can do to hurt yourself.

- I guarantee people will be shocked.

- They will be shocked.

- Oh, yes.

- Well get ready to be shocked tomorrow.

And you can dial 1-800-700-7000,

and you can ask for this andwe'll send it to you free,

how about that?

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