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Dr. Aaron Tabor
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Soy’s Powerful Antioxidant Benefits

By Aaron Tabor, M.D.
CEO and Medical Research Director for Revival Soy - During each day of our lives, we are exposed to oxidative stress. Our bodies produce free radicals, unstable molecules that cause harm to our body’s cells as a by-product of normal metabolism. Exposure to a variety of environmental factors, such as cigarette smoke and environmental pollutants, also increases our susceptibility to free radicals.

The resulting oxidative damage has been implicated in a number of chronic health conditions. Therefore, it is important to consume adequate amounts of dietary antioxidants to reduce the oxidative stress and maintain overall health.

A growing amount of cell culture/test tube (1-3), animal(4-6), and human (7-12) research suggests that the isoflavones in soy are powerful antioxidants. Studies have reported that soy isoflavones alone (1) and in combination with vitamin C (2) reduce the oxidation of plasma LDL cholesterol. Scientific research has also suggested that soy consumption reduces plasma LDL cholesterol oxidation— the oxidation process turns bad LDL into a form that is even worse! (4) —and inhibits oxidative damage to the skin (5).

Several human clinical studies have demonstrated the beneficial antioxidant effects of soy. In one study, it was reported that higher amounts of isoflavones reduced lipid oxidation to a greater extent than low isoflavone amounts (7). Other studies have shown that soy isoflavones reduce markers of oxidative damage (8-10) and improve total antioxidant status (10-11). Furthermore, in a study of breast cancer survivors, consumption of soy isoflavones increased the antioxidant enzyme superoxide dismutase (12). Overall, these studies suggest that adding soy to your diet may help to support better antioxidant status.

So, while many forms of stress can alter your health and outlook on life through oxidative damage, including antioxidants from soy isoflavone-rich foods and supplements in your daily diet can help to reduce the effects of everyday stress.

Revival Soy makes getting enough soy simple and delicious. With Revival Soy, you can be sure you’re getting enough soy isoflavones in your daily diet—without the soy taste. And you can take comfort in knowing you’re using the #1 doctor-recommended soy protein supplement, backed by clinical studies and many patented benefits.

Just 1 small Revival shake or protein bar gives you the amount of soy isoflavones found in 6 cups of a typical soymilk (160 milligrams). A recent panel of international soy experts recommended up to 160 milligrams of soy isoflavones per day for all of the health benefits of soy.

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  1. Hodgson JM, Croft KD, Puddey IB, Mori TA, Beilin LJ.  Soybean isoflavonoids and their metabolic products inhibit in vitro lipoprotein oxidation in serum.  Journal of Nutritional Biochemistry 1996; 7:664-669.

  2. Hwang J, Sevanian A, Hodis HN, Ursini F.  Synergistic inhibition of LDL oxidation by phytoestrogens and ascorbic acid.  Free Radical Biology & Medicine 2000; 29:79-89.

  3. Rimbach G, De Pascual-Teresa S, Weins BA, Matsugo S, Uchida Y, Minihane AM, Turner R, Vafeiadou K, Weinberg, PD.  Antioxidant and free radical scavenging activity of isoflavone metabolites.  Xenobiotica 2003; 33:913-925.

  4. Damasceno NRT, Goto H, Rodrigues FMD, Dia CTS, Okawabata FS, Abdalla DSP, Gidlund M.  Soy protein isolate reduces the oxidizability of LDL and the generation of oxidized LDL autoantibodies in rabbits with diet-induced atherosclerosis.  Journal of Nutrition 2000; 130:2641-2647.

  5. Wei H, Zhang X, Wang Y, Lebwohl M.  Inhibition of ultraviolet light-induced oxidative events in the skin and internal organs of hairless mice by isoflavone genistein.  Cancer Letters 2002; 185:21-29.

  6. Aoki H, Otaka Y, Igarashi K, Takenaka A.  Soy protein reduces paraquat-induced oxidative stress in rats.  Journal of Nutrition 2002; 132:2258-2262.

  7. Wiseman H, O’Reilly JDO, Adlercreutz H, Mallet AI, Bowey EA, Rowland IR, Sanders TAB.  Isoflavone phytoestrogens consumed in soy decrease F2-isoprostane concentrations and increase resistance of low-density lipoprotein to oxidation in humans.  American Journal of Clinical Nutrition 2000; 72:395-400.

  8. Djuric Z, Chen G, Doerge DR, Heilbrun LK, Kucuk O.  Effect of soy isoflavone supplementation on markers of oxidative stress in men and women.  Cancer Letters 2001; 172:1-6.

  9. Davis JN, Kucuk O, Djuric Z, Sarkar FH.  Soy isoflavone supplementation in healthy men prevents NF-kB activation by TNF-a in blood lymphocytes.  Free Radical Biology & Medicine 2001; 30:1293-1302.

  10. Chen CY, Bakhiet RM, Hart V, Holtzman G.  Isoflavones improve plasma homocysteine status and antioxidant defense system in healthy young men at rest but do not ameliorate oxidative stress inducedc by 80% VO2pk exercise.  Annals of Nutrition & Metabolism 2005; 49:33-41.

  11. Bazzoli DL, Hill S, DiSilvestro RA.  Soy protein antioxidant actions in active, young adult women.  Nutrition Research 2002; 22:807-815.

  12. DiSilvestro RA, Goodman J, Dy E, LaValle G.  Soy isoflavone supplementation elevates erythrocyte superoxide dismutase, but not ceruloplasmin in postmenopausal breast cancer survivors.  Breast Cancer Research and Treatment 2005; 89:251-255.

REVIVAL IS A DIETARY SUPPLEMENT: These statements have not been evaluated by the Food and Drug Administration. Revival is not intended to diagnose, treat, cure or prevent any disease. MEDICAL DISCLAIMER: All information is intended for your general knowledge only and is not a substitute for medical advice or treatment for specific medical conditions. We can not and do not give you medical advice.

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